My uncle has PD and started taking LDN in September 2002. For years we insisted it stopped his progression but he always told us he could feel progression. His PD is progressing slowly so maybe the LDN is helping in that respect. None of us can deny that he is progressing any longer as his tremors are throughout his body. I called Dr Bihari and he told me that he discovered a few years ago that sadly LDN does not halt Parkinson's like he hoped it would. His other PD patients also progressed he said. My uncle still takes LDN but it does not work for PD like it does for MS. My husband with PPMS has not experienced one brand new symptom since he started LDN in September 2002.
Mary and Sam, sometimes PD symptoms are caused by Lyme
The new kid on the block is Borrelia Burgdorferi (Bb) and some of us have looked at it for a long time as possibly the bug that opens the door for all the other infections to enter the system. Lyme disease has become a buzzword in the alternative medical field.
Many patients with MS, ALS, Parkinson’s disease, autism, joint arthritis, chronic fatigue, sarcoidosis and even cancer are infected with Borrelia burgdorferi. But is the infection causing the illness or is it an opportunistic infection simply occurring in people weakened by other illnesses.
Conditions most commonly seen with Lyme disease include Alzheimer's disease, amyotrophic lateral sclerosis (ALS), chronic fatigue syndrome (CFS), fibromyalgia, irritable bowel syndrome, lupus, rheumatoid arthritis, scleroderma, multiple sclerosis (MS), Parkinson's disease and various autoimmune disorders.
Borrelia Burgdorferi(Bb) tends to infect the B-lymphocytes and other components of the immune system which are responsible for creating the antibodies, which are then measured by an ELISA test or Western Blot test. Since antibody production is greatly compromised in infected individuals, it makes no sense to use these tests as the gold standard or benchmark for the presence of Bb (7). We also are aware that in endemic areas in the US up to 22% of stinging flies and mosquitoes (2, 8, 9,10) are carriers of Bb and co-infections. In South East Germany and Eastern Europe, 12 % of mosquitoes have been shown to be infected. Also many spiders, flees, lice and other stinging insects carry spirochetes and co-infections.
Making the history of a tick bite a condition for a physician to be willing to even consider the possibility of a Bb infection seems cynical and cruel.
To use conventional diagnostic tests such as the Western Blot, one has to think in paradoxes: the patient has to be treated with an effective treatment modality first before the patient recovers enough to produce the antibodies, which then are looked for in the test. A positive Western Blot proves that the treatment given worked to some degree.
A negative Western Blot does not and cannot prove the absence of the infection.
Having taken another route altogether, we have recognized the following:
Today many if not most Americans are carriers of the infection. Most infected people are symptomatic, but the severity and type of the symptoms varies greatly. The microbes often invade tissues that had been injured: your chronic neck pain or sciatica really may be a Bb infection. The same may be true for your chronic TMJ problem, your adrenal fatigue, your thyroid dysfunction, your GERD and many other seemingly unrelated symptoms.
In most places the diagnosis of an active Bb infection is made only, if the symptoms are severe, persistent, obvious.
BEST LYME DIAGNOSTIC TOOL. FIND A DOCTOR WITH THE BRADFORD VARIABLE PROJECTION MICROSCOPE in or around your city.
Bradford High Resolution Microscopy
(Bradford Variable Projection Microscope): Both the cyst and spirochete forms in the three different morphologies are easily identified with resolutions less than 0.1 micron with concurrent magnification of 10,000x utilizing dark-field and phase contrast modes.
Comparison of Tests: High Resolution Microscopy is the most reliable test........ PCR, Western Blot and ELISA are the LEAST reliable with up to 80% false-negatives (CDC Guidelines).
Comparison of Detection Methods
The Centers for Disease Control (CDC) in Atlanta, Georgia, has issued guidelines for Lyme patients, advising them of a recommended protocol in attempting to establish whether Lyme disease is present or not. Doctors have been instructed by these guidelines to obtain an ELISA test first, which, under the best circumstances, identifies only 40-50% of those who actually have Lyme disease. An ELISA should NOT be used as a screening test due to the unreliable results. The guidelines then state that, if the ELISA test is positive, doctors are to perform the Western Blot test. This procedure allows many cases of Lyme disease to be missed, therefore patients are not being identified or properly treated. The CDC guidelines also state which specific bands on a nitrocellulose strip are to be used in considering a test positive. When the list of bands was developed, certain bands specific for Lyme disease were not included. When these bands are positive, they confirm exposure to the causative organism, but it is mistakenly reported to the doctor and patient as a "negative test." Many borderline tests are reported to patients as being negative and many positive tests are reported to be "false-positive" because doctors are not familiar with reading test results, nor with the multiple symptoms that can occur in a person with Lyme disease.
Solution to Detection Problem
The Bradford High Resolution Blood Morphology imaging, known as Bradford Variable Projection Microscope of both Lyme spirochete and cyst forms have proven to be highly accurate.
The various cyst forms are found in B-cells, eosinophils, basophils, with and without the spirochete.
The detection of Lyme disease by the Bradford High Resolution Microscope is highly correlated with the Fluorescent Antibody Test (FDA-licensed Bowen Laboratories, Florida)